بررسی تأثیر شیاف واژینال پروستاگلاندین E2 در القای زایمان با اکسی‌توسین در بارداری طول کشیده

Unfavorable cervix is a major problem in termination of prolonged pregnancies. It is one cauese of increased cesarean section rate in these pregnancies. Prosta glandines are used for cevical ripening. In this randomized controlled trial, two groups with post term pregnancy and unfavorable cervix each included 50 patients underwent induction of labor with oxytocin. In the case group, prostaglandin suppository was used intravaginally 8 hours before induction. In this group Bishop score increased(0.75±0.69 vs 2.39±0.84)(P<0.005), and the time from beginning of induction to delivery was shorter than control group 574.8±280.1 vs 843.04±412.8 min)(P<0.005). C/S rate was the same intwo groups. The only side effect of PGE2 was nausea. It can be concluded that PGE2 vaginal suppoditory is useful for ripening of cervix and decreasing the duration of induction withoutserious side effects.